¿Ha olvidado su contraseña?
¿Nuevo usuario?
Todas las páginas de contenido de AbM.objectis.net
Resumen de literatura científica de alto índice de impacto sobre el Agaricus blazei Murill o champiñón del Sol
Acciones de Documento
Blazein of a new steroid isolated from Agaricus blazei Murrill (himematsutake) induces cell death and morphological change indicative of apoptotic chromatin condensation in human lung cancer LU99 and stomach cancer KATO III cells
2008 - La blazeína (Blazein) de un nuevo esteroide aislado del Agaricus blazei Murill (himematsutake) induce la muerte celular y cambios morfológicos indicativos de condensación cromatina apoptótica en las células humanas de cáncer de pulmón LU99 y de cáncer de estómago KATO III.
Oncol Rep. 2008 Dec;20(6):1359-1361
Faculty of Bioresources, Mie University, Mie 514-0001, Japan.
Blazein was isolated from mushroom (Agaricus blazei Murrill) and identified by Mass and 1H-NMR as blazein. The effect of blazein on the DNA of human various cancer cells was investigated. DNA fragmentations by blazein to oligonucreosomal-sized fragments, a characteristic of apoptosis, were observed in the human lung LU99 and stomach KATO III cancer cells. The DNA fragmentations by blazein were observed from day 2 (KATO III cells) or day 3 (LU99 cells) after the addition of blazein to the culture cells. These findings suggest that growth inhibition by blazein results from the induction of apoptosis by the compound.
Dos nuevos trabajos científicos sobre los mecanismos de la apóptosis y actividad antimetastática inducidos por Agaricus blazei Murill o champiñón del sol