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Resumen de literatura científica de alto índice de impacto sobre el Agaricus blazei Murill o champiñón del Sol
Acciones de Documento
Effect of hot water extract from Agaricus blazei Murill on antibody-producing cells in mice
2002 - Efectos de extractos de agua caliente del Agaricus blazei Murill en la producción de células de anticuerpos en ratones.
- Int Immunopharmacol. 2002 Jul;2(8):1205-11.
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Effect of hot water extract from Agaricus blazei Murill on antibody-producing cells in mice.
Department of Biotechnology, Faculty of Engineering, Kyoto Sangyo University, Japan.
We investigated the immunopotentiating activities of boiled water-soluble extracts from desiccated Agaricus blazei Murill (ABM). Effect of ABM extract on antibody production was investigated by method of hemolytic plaque-forming cells (PFC) against sheep red blood cells (SRBC) antigen. ABM extracts significantly (p<0.01) increased the number of PFC in spleen with intraperitoneal administration at doses of 25 mg/kg as compared with control group. The populations of Mac-1- or CD25-positive cells significantly (p<0.01, p<0.001) increased, but in CD19-positive cells, there were no differences in ABM-treated mice as compared with control mice. The expressions of IL-6 and IL-1beta mRNA were augmented by ABM extract in both peritoneal macrophages and spleen cells. These results suggested that ABM extract might be an effective stimulator for T cell and macrophage to IL-1beta and IL-6 release, resulting in augmentation of antibody production against SRBC antigen.
Un bastante completo artículo de revisión sobre la calidad de alimento funcional del Agaricus blazei en blazei.org