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Effect of an extract of the mushroom Agaricus blazei Murill on expression of adhesion molecules and production of reactive oxygen species in monocytes and granulocytes in human whole blood ex vivo
Acciones de Documento
Polysaccharides from Agaricus blazei stimulate lymphocyte T-cell subsets in mice
1998 - Poliscáridos del Agaricus blazei estimulan los subconjuntos de células de linfocitos T en ratones.
- Biosci Biotechnol Biochem. 1998 Mar;62(3):434-7.
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Polysaccharides from Agaricus blazei stimulate lymphocyte T-cell subsets in mice.
Division of Science of Biological Resources, Graduate School of Science and Technology, Kobe University, Japan.
Subset analysis of splenic lymphocytes using flow cytometry showed that the percentages of Thy1.2-(pan T-cells), L3T4-(CD4, helper T-cells), and Lyt2-(CD8, cytotoxic T-cells) positive cell populations were significantly increased in mice orally administered a hot water-soluble fraction from Agaricus blazei as compared with mice treated only with saline. 13C-NMR data indicates that the main component in the active polysaccharide is the complex of alpha-1,6- and alpha-1,4-glucan, which had already been shown to have anti-tumor activity against Sarcoma 180. It seems that the polysaccharide from Agaricus blazei may be an effective prophylactic, protecting humans against cancer by stimulating lymphocytes such as cytotoxic T-cells.
Un nuevo trabajo sobre el potencial tremendo de un polisacárido de bajo peso molecular del Agaricus blazei en el tratamiento de metástasis neoplásicas y gruesos errores de la publicidad de muchos sitios sobre este champiñón del sol